EMS Neurological Emergencies - Seizure Disorder Treatments

The treatment for seizures depends on several factors, including the type of seizure, underlying cause, and individual patient characteristics. 

Here are some common treatments for seizures:

Antiepileptic Medications (AEDs): Antiepileptic drugs (AEDs) are the mainstay of treatment for epilepsy and other seizure disorders. These medications work by stabilizing electrical activity in the brain and reducing the likelihood of seizures. 

There are many different types of AEDs available, and the choice of medication depends on factors such as the type of seizure, patient age, comorbidities, and potential side effects. Examples of AEDs include carbamazepine, valproate, levetiracetam, lamotrigine, and phenytoin.

Lifestyle Modifications: Certain lifestyle modifications can help reduce the frequency and severity of seizures in some individuals. These may include:

Getting an adequate amount of sleep and maintaining a regular sleep schedule.

Avoiding triggers that may provoke seizures, such as stress, flashing lights, or certain medications.

Following a healthy diet, such as the ketogenic diet, which is high in fat and low in carbohydrates and has been shown to be beneficial for some people with epilepsy.

Limiting alcohol consumption and avoiding recreational drugs.

Surgery: For some individuals with epilepsy that is not well-controlled with medications, surgery may be an option. Surgical procedures such as resective surgery (removing the part of the brain responsible for seizures), laser ablation, or implantation of devices like vagus nerve stimulators or responsive neurostimulation systems can significantly reduce or eliminate seizures in certain cases.

Vagus Nerve Stimulation (VNS): Vagus nerve stimulation (VNS) is a surgical procedure in which a device is implanted under the skin of the chest and connected to the vagus nerve in the neck. 

The device delivers electrical impulses to the vagus nerve at regular intervals, which can help reduce seizure frequency and severity in some individuals with epilepsy.

Responsive Neurostimulation (RNS): Responsive neurostimulation (RNS) is a newer treatment option for epilepsy that involves the implantation of a device in the brain that detects abnormal electrical activity and delivers electrical stimulation to prevent seizures from occurring.

Ketogenic Diet: The ketogenic diet is a high-fat, low-carbohydrate diet that has been shown to be effective in reducing seizures in some individuals with epilepsy, particularly children with certain types of epilepsy syndromes.

Biofeedback & Relaxation Techniques: Some individuals with seizures may benefit from biofeedback training or relaxation techniques, which can help reduce stress and improve overall well-being.

Medication Adjustments: For individuals already taking antiepileptic medications, adjusting the dosage or switching to a different medication may be necessary if seizures are not adequately controlled or if side effects are problematic.

It's important for individuals with seizures to work closely with their healthcare providers to develop a comprehensive treatment plan tailored to their specific needs and circumstances. 

Regular monitoring and adjustments to treatment may be necessary to achieve optimal seizure control and improve quality of life.

Further Reading:

Bledsoe, B. E., Cherry, R. A. & Porter, R. S (2023) Paramedic Care: Principles and Practice (6th Ed) Boston, Massachusetts: Pearson

Huff, J.S. & Murr, N (2023) Seizure. Treasure Island, Florida: StatPearls Publishing https://www.ncbi.nlm.nih.gov/books/NBK430765/ Accessed April 24, 2024

Peate, I. & Sawyer, S (2024) Fundamentals of Applied Pathophysiology for Paramedics. Hoboken, New Jersey:  Wiley Blackwell